How the mitochondrial fusion/fission machinery is regulated, what causes changes in mitochondrial localization, what senses and instructs lineage-specific differential mitochondrial mass accumulation and maintenance, and what factors facilitate transitions in metabolism and cell fates remains a significant area of ongoing and future investigations. PSC metabolism regulates the activities of epigenetic … Continue reading How the mitochondrial fusion/fission machinery is regulated, what causes changes in mitochondrial localization, what senses and instructs lineage-specific differential mitochondrial mass accumulation and maintenance, and what factors facilitate transitions in metabolism and cell fates remains a significant area of ongoing and future investigations